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Endocrine Abstracts

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ea0058oc4.1 | Oral Communications 4 | BSPED2018

Hydrocortisone granules in capsules for opening: phase 3 trial in children with adrenal insufficiency and long-term safety data

Lewis Alexander , Neumann Uta , Wiegand Susanna , Krude Heiko , Digweed Dina , Voet Bernard , Ross Richard , Davies Madhu , Blankenstein Oliver

Introduction: Children with adrenal insufficiency requiring hydrocortisone rely on compounded adult medication. This study aimed to evaluate the absorption, palatability and safety of Alkindi® (hydrocortisone granules in capsules for opening).Methods: The phase 3 study was an open-label, single-dose study in a total of 24 children (aged 0–6 years) with adrenal insufficiency. Fasted children were given a single dose of Alkindi&#1...
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ea0065ja5 | Society for Endocrinology Journal Award – Clinical Endocrinology | SFEBES2019

Absorption and tolerability of taste-masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency

Neumann Uta , Whitaker Martin J , Wiegand Susanna , Krude Heiko , Porter John , Davies Madhu , Digweed Dena , Voet Bernard , Ross Richard J , Blankenstein Oliver

Clinical Endocrinology, 2018, 88(1): 21–29 (DOI: https://doi.org/10.1111/cen.13447)...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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